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Stop by the ALZET booth during one
of these upcoming exhibits in 2008:
EACR
Lyon, France
July 5-8
Exhibit: A9
FENS
Geneva, Switzerland
July 13-16
Exhibit: 405
Complete
2008 schedule
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“Nonspecific toxicity is a common problem associated with in vivo application of antisense oligonucleotides.However, by employing certain strategies including the use of partial rather than complete phosphorothioate modification, reducing the length of the oligonucleotide, and using a steady continuous infusion rather than bolus injections, we were able to minimize such toxicity (Van Kampen & Stoessl, 2000a).” (p. 309) Van Kampen et al., Neuroscience 2003;116:307-314. |
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ALZET®
Osmotic Pumps are miniature, infusion pumps for the continuous
dosing of laboratory animals as small as mice and young rats.
These minipumps provide researchers with a convenient and reliable
method for controlled agent delivery in vivo.
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ALZET®
Osmotic Pumps require no external connections or researcher intervention
during the entire delivery period. Their unique design helps researchers
save critical time by eliminating the need for frequent animal
handling and repetitive injection schedules. These dependable
drug delivery systems have proven invaluable in predictably sustaining
compounds at therapeutic levels, avoiding potentially toxic or
misleading side effects and ensuring accurate research results.
An assortment of sizes, flow rates and durations is available
to meet a variety of research needs. A single ALZET pump provides
up to 6 weeks of continuous infusion.
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Download
the Neuroscience focus Newsletter

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Neuroscience
Research ALZET pumps are used in
neuroscience research as an essential method to overcome the blood-brain
barrier and deliver neuroactive compounds to the CNS. ALZET pumps and Brain
Infusion Kits have been instrumental to the study of neurodegenerative
diseases, cognitive research, neuroprotection, spinal cord injury,
cerebral ischemia, and more.
Click here for more
information on the use of ALZET pumps in neuroscience.
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